Nuggets of Knowledge – Intro to Infectious Diseases

Few tidbits from the ADS on ID.

  • Presence of polymorphonuclear cells (PMNs) indicates inflammation
  • Beware of epithelial cell contamination in a sample
  • Coagulase-negative Staphylococcus spp is often a contaminant of blood cultures
  • A C&S will NEVER have PO susceptibility data due to concerns with bioavailability. Consult microbiology if you need direction.
  • Eosinophilia increases suspicion of allergic reactions or parasitic infections
  • Lymphocytosis increases suspicion of malignancy or bacterial infections
  • Acute phase reactants are non-specific but add to the overall picture
  • Pearl: cellulitis treated with ABX will appear to worsen for 2-3 days due to killing of bacteria and subsequent release of endotoxins
  • Some antibiotics perform poorly in acidic environments, so therefore will not penetrate and treat an abscess.
  • When do you consult microbiology?
    • Need more specific identification on an organism
    • Need additional susceptibility or MIC data
    • Need guidance on which test to use to identify a bug

And of course, this fun gem:

10commandmentsID

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